About Haemophilia

Haemophilia A is a rare, inherited bleeding disorder caused by deficiency of blood coagulation factor VIII (FVIII), affecting ~ 1 in 5,800 males. People with haemophilia bleed longer and more easily than other people; the frequency and severity of bleeds is dependent on the severity of the disease, which can vary from mild or moderate to severe. Replacement with (plasma/recombinant) human FVIII has been a standard of care treatment now for many years for haemophilia A. Worldwide, approximately 70% of all (prevalent) patients – approximately 430,000 patients- are untreated, according to the Annual Global Survey report  from the World Federation of Hemophilia (WFH). 90% of all untreated patients live in underdeveloped countries, with one of the key hurdles being the access to an affordable haemophilia treatment.