ProFactor Pharma Limited (PFP) is a UK based company formed in 2009 by Professor J H McVey and Dr Ian Garner, who had been working with recombinant human Factor VIII (rhFVIII) for over 25 years, together with Co-founders Richard Cruse, Bruce Vernon and Hugh Ilyine building a team with many years of biotech experience.
Factor VIII is a large, complex and inherently unstable protein, requiring particular skills and know-how in its handling and production. PFP has these skills.
PFP has developed a patent protected, commercially attractive, Good Manufacturing Practice (GMP) compatible cell-line and low cost production process for making rhFVIII. The process has been optimised and final product manufactured for toxicology studies. Clinical trials are planned to commence before the end of 2021.