PFP has developed a patent protected way to make recombinant Factor VIII in a bioprocess delivering 10 times higher yields than the industry standard, at a much lower cost of goods.
We have been able to achieve this superior yield with lower cost of goods by combining a proprietary high expressing cell line (Patent Applied for) with innovative single use disposable manufacturing technology. Modern downstream purification technologies (Patent Applied for) are also more efficient leading to a high yield of final product.
Based on the expression data, our manufacturing model suggests a single 100L Single Use fermenter could produce 150 million International Units of rhFVIII per year. And this process is eminently scalable. A 1,000L fermenter could produce 1.5 billion IUs. This would represent an increase of 20% over the current world production of ~5BN IUs.